Country GuideMedical AccessMedical Only (Private)

Country Access Report

Medical Access and Reimbursement in Comoros

Comoros is a party to international drug‑control treaties and maintains strict national controls over psychotropic and narcotic substances; there is no public reimbursement pathway or established national medical psychedelic program. Ketamine is the only compound with a well‑established recognized medical role (primarily as an anaesthetic) and is widely listed on WHO essential medicine guidance, whereas classic psychedelics (psilocybin, MDMA, DMT, mescaline, ibogaine, 5‑MeO‑DMT, ayahuasca, 2C‑X) and esketamine have no authorized medical reimbursement or formal national access pathways outside of tightly regulated research or criminal prohibitions. The Union of the Comoros is a party to the UN drug control conventions, which forms the baseline for national control measures. [https://treaties.un.org/Pages/ViewDetails.aspx?src=IND&mtdsg_no=VI-16&chapter=6&clang=_en|UN Treaty Collection - Convention on Psychotropic Substances] [https://api.parliament.uk/UKTreaties/4191|Single Convention accession record for Comoros]

Access Level
Medical Only (Private)
Compounds Covered
10
Active Trials
0

Access by Compound

Compound-specific notes summarise what is realistically available through approved medical use, clinical research, exceptional access, or private care where the country report has verifiable information.

Compound Access

Psilocybin

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. The Union of the Comoros is party to international drug control treaties that require control of psychotropic substances, which underpin national prohibition of non‑medical uses. #

Compound Access

MDMA

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. There is no evidence of an established national medical program, licensing, or reimbursement for MDMA‑assisted therapy in the Comoros; access would be limited to approved international clinical trials if any occur. #

Compound Access

Esketamine

Clinical Trials Only / Strictly Controlled

Currently classified under controlled‑substance frameworks with no publicly documented national approval, reimbursement, or registered product authorization for esketamine (Spravato®) in the Comoros. There is no indication of a national regulatory approval or public reimbursement pathway for esketamine; any access would therefore be limited to participation in an approved clinical trial or import under special authorization if permitted. The broader international treaty obligations inform national control measures. # #

Compound Access

Ketamine

Medical (Anaesthetic) — Not Reimbursed for Psychedelic Indications

Ketamine is listed on the World Health Organization Model List of Essential Medicines for use as an injectable general anaesthetic and is widely used internationally in low‑ and middle‑income health systems for surgical and emergency anaesthesia; this WHO listing supports routine medical availability of ketamine in many countries, including resource‑limited settings. #

In the Comoros there is no public information indicating a national, publicly funded reimbursement program for ketamine when used for investigational or off‑label psychiatric indications (for example, treatment‑resistant depression). Available evidence and standard practice in similar health systems indicate that ketamine’s primary lawful medical use in the country would be as an anaesthetic or procedural sedative provided within hospitals or clinical facilities; procurement and use for these indications are typically handled through hospital budgets, private providers, or donor/NGO supplies rather than a dedicated reimbursed mental‑health program. There is no publicly available regulatory approval notice, national formulary listing, or Ministry of Health guidance showing ketamine is reimbursed for psychiatric indications in the Comoros. #

Operationally this means: ketamine is likely available and lawfully used in medical/surgical settings (consistent with WHO essential‑medicines guidance), but there is no structured national reimbursement pathway or formal program in Comoros for ketamine‑based psychiatric treatment; off‑label psychiatric uses would therefore be ad hoc, clinician‑led, and not publicly reimbursed. (If you require confirmation of hospital‑level availability or procurement mechanisms in a specific Comorian hospital or region, I can look up national procurement lists or contactable ministry documents.) #

Compound Access

DMT

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. There is no public record of national medical authorization or reimbursement for DMT in the Comoros. #

Compound Access

5-MeO-DMT

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. No national authorization or reimbursement pathway has been identified for 5‑MeO‑DMT in Comoros. #

Compound Access

Ibogaine

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. There is no public evidence of regulated medical or reimbursed ibogaine treatment availability in the Comoros. #

Compound Access

Ayahuasca

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. Traditional plant‑based preparations containing DMT (commonly referred to as ayahuasca) would be controlled under the same national controls applicable to DMT and similar psychotropics. #

Compound Access

Mescaline

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. There is no evidence of a national medical or reimbursed program for mescaline in the Comoros. #

Compound Access

2C-X

Strictly Illegal

Currently classified as a strictly controlled substance under national drug‑scheduling laws, with no authorized medical use outside of approved clinical research. Novel phenethylamines (the 2C family) are controlled under international and national psychotropic substance controls and are not authorized or reimbursed for medical treatment in the Comoros. #

Sources and Verification

Last updated 2 Mar 2026. Source links are drawn from citation annotations in the medical access and reimbursement guide.

  1. 1EMA - Spravato (for context on where product authorizations exist internationally)
  2. 2UN Treaty Collection - Convention on Psychotropic Substances
  3. 3WHO Model List of Essential Medicines
  4. 4WHO Model List of Essential Medicines - Ketamine entry