Ketamine is widely recognised on the WHO Model List of Essential Medicines as an injectable anaesthetic, indicating its importance in medical care globally; however, in Djibouti all narcotic/psychotropic importation, possession and distribution are governed by strict national controls (Loi No. 171/AN/81). This means any legitimate medical use of ketamine in Djibouti would be subject to licensing, importation controls and oversight by health authorities; there is no publicly available evidence of a formal national reimbursement program for ketamine for psychiatric indications (e.g., for depression). Routine hospital use of ketamine as an anaesthetic is consistent with global practice where ketamine is included on essential medicines lists, but local prescribing, procurement and any insurance coverage would follow Djiboutian Ministry of Health procedures and narcotics regulation. Sources: WHO listing of ketamine on the Model List of Essential Medicines; Djibouti national psychotropic substances law. #; #