Medical Only (Private)

Reimbursed Care Access in Nigeria

Nigeria maintains a highly restrictive national drug control regime: classical psychedelics and novel psychoactive tryptamines/phenethylamines are effectively prohibited for general use and only accessible in tightly controlled research settings. Medical and legally reimbursed access is limited to established medicines (e.g., ketamine as an anaesthetic), which are prescription-only and regulated by NAFDAC; there is no evidence of marketed esketamine (Spravato) registration or public reimbursement for psychedelic-assisted psychiatric care. Enforcement and criminal penalties for possession, trafficking or unauthorised use of psychotropic substances are severe under the NDLEA framework.

Psilocybin

Strictly Illegal

Currently classified as a strictly controlled substance under Nigeria's national drug control laws, with no authorized medical use outside of approved clinical research. Possession, trafficking and unauthorised use of psychotropic substances are criminalised under the National Drug Law Enforcement Agency (NDLEA) Act and subject to severe penalties. # #

MDMA

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. Enforcement actions for trafficking and possession are pursued by NDLEA and carry heavy sentences under Nigerian law. # #

Esketamine

Not Registered / Not Reimbursed

No evidence of a NAFDAC marketing authorisation or registered Spravato (esketamine) product was found in the NAFDAC product registry; therefore esketamine is not an available, reimbursed treatment in routine Nigerian clinical care. Ketamine (racemic) injections are registered as prescription-only medicines in Nigeria and are available for anaesthesia/acute clinical use under NAFDAC oversight, but esketamine (the Janssen nasal spray marketed as Spravato) does not appear on NAFDAC listings and is not publicly documented as approved or covered by public insurance. # #

Ketamine

Prescription-only (In-use, Off-label Psychiatric Use Not Reimbursed)

Ketamine hydrochloride is a registered, prescription-only medicine in Nigeria and is marketed/authorised for clinical use (principally as an anaesthetic); NAFDAC records show approved injectable ketamine products on the national registry. In practice, ketamine is available in public and private hospitals for anaesthesia and emergency medicine under standard medical regulation, but there is no established, publicly reimbursed program for ketamine-based psychiatric treatment (e.g., for treatment‑resistant depression) akin to structured, insured esketamine programs found in some other countries. Off-label psychiatric use would therefore occur on a case-by-case basis in private clinical practice (if practised) and is unlikely to be covered by public insurance; any such use must comply with medicine regulations and professional guidance. # #

DMT

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. NDLEA enforcement covers psychotropic tryptamines, and possession/trafficking is criminalised with severe penalties. # #

5-MeO-DMT

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. There is no recognized clinical or reimbursed pathway for 5‑MeO‑DMT in Nigeria. # #

Ibogaine

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. While ibogaine occupies grey zones in some jurisdictions internationally, in Nigeria the NDLEA criminal framework offers no authorised, reimbursed medical pathway for ibogaine-assisted treatment. # #

Ayahuasca

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. Preparations containing DMT (the principal active constituent in ayahuasca brews) fall under the NDLEA control regime and are not subject to any recognised, reimbursed medical programme in Nigeria. # #

Mescaline

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. Mescaline-containing cacti and purified mescaline are covered by Nigeria's psychotropic controls and are not legally available for medical reimbursement. # #

2C-X

Strictly Illegal

Currently classified as a strictly controlled substance under national drug scheduling laws, with no authorized medical use outside of approved clinical research. Novel phenethylamine psychedelics (2C series and related compounds) are treated as illicit psychotropic substances under NDLEA enforcement. # #