Country GuideMedical AccessPublic Esketamine + Research Only

Country Access Report

Medical Access and Reimbursement in Poland

Poland remains restrictive for classical psychedelics, which are generally research-only under Group I-P controls. The clearest patient-access route is EU-authorised esketamine through NFZ drug programme B.147 for treatment-resistant depression. Ketamine is legally available as a medical anaesthetic and appears in off-label psychiatric research and practice, but no routine public reimbursement route for antidepressant ketamine was identified.

Access Level
Public Esketamine + Research Only
Compounds Covered
10
Active Trials
4

Access by Compound

Compound-specific notes summarise what is realistically available through approved medical use, clinical research, exceptional access, or private care where the country report has verifiable information.

Compound Access

Psilocybin

Research-only controlled substance

Psilocybin and psilocin are treated as Group I-P psychotropic substances. Under the Polish framework, that supports research-only use rather than routine medical prescribing or reimbursement. # #

Compound Access

MDMA

Research-only controlled substance

MDMA remains controlled in Poland and no authorised medical or public reimbursement route was identified. Lawful use should be treated as limited to authorised research. # # #

Compound Access

Esketamine

EU-authorised; publicly reimbursed in B.147

Esketamine is the clearest Polish patient-access route. Spravato is EU-authorised and Polish procurement/reimbursement evidence identifies esketamine as reimbursed under drug programme B.147 for treatment-resistant depression. # # #

Compound Access

Ketamine

Medical anaesthetic; off-label psychiatry not nationally reimbursed

Ketamine is listed separately from Group I-P psychedelics and can be used medically, but Polish psychiatric use for depression remains off-label. Reviewed sources did not show a national public reimbursement route for antidepressant ketamine. # # #

Compound Access

DMT

Research-only controlled substance

DMT remains controlled in Poland. No authorised routine medical access or reimbursement pathway was identified outside approved research. # #

Compound Access

5-MeO-DMT

Research-only; GH001 trial-linked signal

5-MeO-DMT is not a routine Polish treatment. Poland is relevant through research links, including the GH001 mebufotenin publication with Medical University of Gdansk authorship, but this does not create patient access. # # #

Compound Access

Ibogaine

No authorised medical access verified

No Polish authorised ibogaine treatment, reimbursement route or strong country-specific clinical programme was identified in the reviewed sources. # #

Compound Access

Ayahuasca

No authorised medical access verified

No Polish authorised medical or reimbursement route for ayahuasca was identified. DMT-related controls and the lack of a specific access pathway mean it should be treated as unavailable outside authorised research. # #

Compound Access

Mescaline

Research-only controlled substance

Mescaline remains a controlled psychotropic substance. No authorised medical or reimbursement pathway was identified outside approved research. #

Compound Access

2C-X

Controlled; no authorised medical access verified

2C-family substances remain controlled in Poland. No authorised treatment or reimbursement route was identified in the reviewed sources. #

Sources and Verification

Last updated 13 May 2026. Source links are drawn from citation annotations in the medical access and reimbursement guide.

  1. 1ClinicalTrials.gov NCT05565352 ketamine registry
  2. 2EMA Spravato EPAR
  3. 3EU public procurement notice for esketamine under B.147
  4. 4JAMA Psychiatry GH001 mebufotenin trial
  5. 5Medical University of Gdansk ketamine publication
  6. 6Polish Act on Counteracting Drug Addiction
  7. 7Polish Ministry of Health reimbursement notices
  8. 8Polish psychotropic and narcotic substance lists
  9. 9PubMed GH001 mebufotenin trial record
  10. 10URPL clinical-trial registration information