Back to journals
Academic Journal

Journal of Psychopharmacology

190 Papers Indexed in Blossom

Published Papers

Open Accessmeta

Trip killers: Addressing a critical knowledge gap in psychedelic research

This review (2026) examines medicines that might be used to stop or reduce severe distress during a psychedelic “bad trip”, focusing on serotonin antagonists, antipsychotics, and some anxiety and depression drugs. It also considers how these drugs work, how quickly they act, their safety, and how they might be used in emergency care.

Published
Journal
Journal of Psychopharmacology
Authors
O’Mahony, B., Harrington, C., Harkin, A., Lally, N.
Open Accessmeta

Roland R. Griffiths, psychopharmacology pioneer: Abuse liability, alcohol, nicotine, caffeine, benzodiazepines, and psychedelics

This review (2026) highlights Roland Griffiths’ major contributions to behavioural and neuropsychopharmacology, particularly his methodical work on abuse liability assessment for alcohol, nicotine, caffeine, and benzodiazepines, alongside his later pioneering research on psychedelics. It also emphasises that his collaborative, mentoring style was central to the development of influential research programmes, including the Johns Hopkins Centre for Psychedelic and Consciousness Research.

Published
Journal
Journal of Psychopharmacology
Authors
Henningfield, J. E., Barrett, F. S., Evans, S. M., Garcia-Romeu, A., Garrett, B. E., Hienz, R. D., Lukas, S. E., Nayak, S. M., Strain, E. C., Weerts, E. M., Yaden, M. E., Yaden, D. B.
Paywallindividual

A randomized clinical trial of repeated doses of psilocybin for the treatment of obsessive–compulsive disorder

This randomised clinical trial (n=15) found that psilocybin (up to 21mg/70kg) given over up to eight weekly sessions was well-tolerated with no serious adverse events, and significantly reduced OCD symptoms compared to placebo, with 73% of participants responding and 40% reaching remission by the end of the 8-week treatment, with meaningful effects still present at 6 months.

Published
Journal
Journal of Psychopharmacology
Authors
Moreno, F. A., Allen, K. E., Wiegand, C. B., Dunne, R., Prickett, J. I., Bayze, B., Allen, J. J. B.
Paywallindividual

A phase 2 uncontrolled, open-label study of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine) in patients with treatment-resistant depression

This 12‑week, open‑label Phase IIa trial of a single 10 mg intranasal dose of 5‑MeO-DMT (BPL‑003) in patients (n=12) with treatment‑resistant major depressive disorder, found that the drug was generally well tolerated with mostly mild–moderate adverse events and rapid discharge readiness (median ~98 minutes). A rapid and sustained mean MADRS reduction of 12–13 points was observed from Day 2 through Day 85, with most participants meeting response criteria and several achieving remission, supporting further evaluation in larger controlled trials.

Published
Journal
Journal of Psychopharmacology
Authors
Roberts, C., Seynaeve, M., Ermakova, A. O., Dunbar, F., Wells, H., Puri, A., Bird, C., Rucker, J. J.
Paywallindividual

The effects of psilocybin on time perception in humans: A comparative analysis of subjective and objective measures

This double-blind placebo-controlled trial (n=24) found that psilocybin changed how healthy volunteers perceived time, making intervals seem slower and less precise on an objective timing task. These effects matched participants’ own reports of time slowing down and were most evident for durations longer than 2 seconds.

Published
Journal
Journal of Psychopharmacology
Authors
Scholle, P., Wenke, Š., Nekovářová, T., Zaytseva, Y., Tylš, F., Brunovský, M., Horáček, J., Andrashko, V., Koudelka, V., Viktorinová, M., Viktorin, V., Hájková, K., Kuchař, M., Páleníček, T.
Paywallindividual

Predicting and exploring ayahuasca effects: Perception, mind-wandering, and EEG oscillations

In a double-blind, placebo-controlled trial of 50 volunteers, ayahuasca produced robust perceptual, emotional and mystical experiences alongside EEG changes (notably reduced global alpha and increased frontomedial delta and right-posterior theta/beta), with acute lower theta linked to stronger mystical effects and baseline theta and beta oscillations predicting interoceptive and emotional responses.

Published
Journal
Journal of Psychopharmacology
Authors
Silva-Costa, N., Pessoa, J. A., Andrade, K. C., Mota-Rolim, S., Palhano-Fontes, F., Araujo, D. B., Wießner, I.

Quick Facts

Papers Indexed
190
h-Index
143
Open Access
No
Publisher
SAGE Publications
Country
United Kingdom
Website
Visit