This case report SPECT imaging study explored the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder (AUD). It reported that the patient felt improvement in mood, cessation of alcohol use, and decreased cravings at 5 days post-treatment, but the patient returned partially to mild alcohol use at 2 months. Also, higher perfusion in multiple brain regions broadly associated with AUD and known pharmacology of both compounds was reported.
- Published
- Journal
- Progress in Brain Research
- Authors
- Barsuglia, J. P., Polanco, M., Palmer, R., Malcolm, B. J., Kelmendi #, B., Calvey, T.