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Psychopharmacology

106 Papers Indexed in Blossom

Published Papers

Open Accessindividual

Psilocybin-induced neurocardiogenic syncope: a case report

This case report describes a healthy 35-year-old man who fainted after taking 25 mg oral psilocybin during an open-label brain function study, with low blood pressure, rapid heartbeat and sweating consistent with neurocardiogenic syncope. He recovered quickly with simple supportive care, highlighting a rare hypotensive reaction during psilocybin administration.

Published
Journal
Psychopharmacology
Authors
Atiq, M. A., Weisman, E., Guerra, R. B., Martinez, L. L., Yaden, D. B., Barrett, F. S., Nayak, S., Sayali, C.
Open Accessmeta

Evaluating the evidence for repressed memory recovery in psychedelic contexts

This scoping review (s=53) examined reports of repressed memory recovery in psychedelic contexts and found that most of the literature focused on LSD, with little agreement on what repressed memory means. It found only limited evidence for proposed psychological or brain-based explanations, and no consistent proof that psychedelics reliably recover repressed memories.

Published
Journal
Psychopharmacology
Authors
Griesfeller, A. F., Kooman, L., Kloft-Heller, L., Kangaslampi, S., Ramaekers, J. G., Otgaar, H.
Open Accessindividual

Blood biomarker changes and relationships after low dose oral ketamine treatment for post-traumatic stress disorder (PTSD)

This open-label trial (n=25) found that six weeks of low-dose oral ketamine treatment for PTSD was associated with small but significant decreases in both BDNF and VEGF-A blood biomarkers, which were positively correlated with each other, suggesting these two proteins may interact as part of the biological mechanism behind ketamine's effects on PTSD symptoms.

Published
Journal
Psychopharmacology
Authors
Quigley, B. L., Orr, E., Kafka, S., Hajishafiee, M., Bouças, A. P., Wellington, N., Dutton, M., Jones, M., Randall, F., Lagopoulos, J., Can, A. T., Hermens, D. F.
Open Accessindividual

Intact neurophysiological markers of death denial in long-term ayahuasca users

Using a no‑report MEG visual mismatch response paradigm, the study found that long‑term ayahuasca users report reduced fear of death and greater life satisfaction, but nonetheless retain intact neurophysiological markers of self‑specific death denial at automatic perceptual levels. The neural denial marker correlated with lower self‑reported death acceptance and reduced accessibility of death‑related thoughts, suggesting ayahuasca alters conceptual and affective engagement with death but not unconscious self‑specific denial.

Published
Journal
Psychopharmacology
Authors
Dor-Ziderman, Y., David, J., Berkovich-Ohana, A.
Paywallindividual

The effect of methamphetamine and 3,4-methylenedioxymethamphetamine on peripheral endocannabinoid concentrations: a study in healthy adults

This within-subject, double-blind study (n=22) found that acute administration of methamphetamine (14 mg/70 kg) significantly lowered plasma 2-arachidonoylglycerol concentrations compared to placebo at 150-180 minutes post-administration, whilst MDMA (100 mg) did not affect endocannabinoid levels, and higher anandamide concentrations during the placebo condition correlated with disliking the 'drug effects'.

Published
Journal
Psychopharmacology
Authors
Mayo, L. M., Haggarty, C. J., Petrie, S. R., Hill, M. N., Bershad, A. K., de Wit, H., Deutch, A. Y.
Open Accessindividual

Moderating factors in psilocybin-assisted treatment affecting mood and personality: A naturalistic, open-label investigation

In a naturalistic, open‑label study a single high dose of psilocybin with psychotherapy produced sustained reductions in depression, anxiety, PTSD symptoms and neuroticism, and increases in openness and conscientiousness at three months. The size of these benefits was moderated by participants’ subjective dosing experiences (mystical‑type experiences, emotional breakthrough and post‑treatment growth) and demographic factors, highlighting variables that may help optimise psilocybin‑assisted treatment.

Published
Journal
Psychopharmacology
Authors
Irrmischer, M., Puxty, D. J., Deijen, J. B., Engelbregt, H., Yildirim, B. O.

Quick Facts

Papers Indexed
106
h-Index
218
Open Access
No
Publisher
Springer Nature
Country
Germany
Website
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