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Academic Journal

Psychophysiology

2 Papers Indexed in Blossom

Published Papers

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Naturalistic use of psychedelics does not modulate processing of self-related stimuli (but it might modulate attentional mechanisms): An event-related potentials study

In a preregistered cross‑sectional ERP study comparing experienced naturalistic psychedelic users (N=56) and non‑users (N=57), P300 amplitude to participants' own names did not differ between groups, indicating no persistent change in self‑representation. Psychedelic users did show increased P300 to other‑names and a smaller task‑related P300 enhancement to target names, consistent with altered allocation of attentional resources.

Published
Journal
Psychophysiology
Authors
Orłowski, P., Hobot, J., Ruban, A., Szczypiński, J., Bola, M.
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LSD and ketanserin and their impact on the human autonomic nervous system

In a randomised, placebo-controlled crossover study using R‑peak-derived HRV, LSD predominantly increased sympathetic activity while pre-treatment with the 5‑HT2A antagonist ketanserin shifted autonomic balance towards increased parasympathetic tone. Sympathetic activation correlated positively (and parasympathetic negatively) with psychedelic intensity, and baseline HRV predicted subjective responses, suggesting trait ANS measures could serve as candidate biomarkers for LSD’s therapeutic effectiveness.

Published
Journal
Psychophysiology
Authors
Olbrich, S., Preller, K. H., Vollenweider, F. X.

Quick Facts

Papers Indexed
2
h-Index
182
Open Access
No
Publisher
Wiley
Country
United States
Website
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