Anxiety DisordersPalliative & End-of-Life DistressDepressive DisordersLSD

Psychedelics and dying care: A historical look at the relationship between psychedelics and palliative care

This review article (2019) retraces the history of psychedelics (specifically LSD) for palliative care and the possibility of reducing (end-of-life) anxiety.

Authors

  • Erika Dyck

Published

Journal of Psychoactive Drugs
meta Study

Abstract

This article examines the historical relationship between psychedelics and palliative care. Historians have contributed to a growing field of studies about how psychedelics have been used in the past, but much of that scholarship focused on interrogating questions of legitimacy or proving that psychedelics had therapeutic potential. Palliative care had not yet developed as medical sub-specialty, more often leaving dying care on the margins of modern, pharmaceutical-based treatments. As psychedelic researchers in the 1950s began exploring different applications for psychoactive substances such as LSD and mescaline, however, dying care came into clearer focus as a potential avenue for psychedelics. Before that application gained momentum in clinical or philosophical discussions, psychedelics were criminalized and some of those early discussions were lost. This article looks back at historical discussions about LSD’s potential for easing the anxiety associated with dying, and considers how those early conversations might offer insights into today’s more articulated discussions about psychedelics in palliative care.

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Research Summary of 'Psychedelics and dying care: A historical look at the relationship between psychedelics and palliative care'

Introduction

The paper situates mid-twentieth century interest in psychedelics within debates about how to care for the dying, noting that early thinkers and clinicians saw psychoactive substances as promising tools for addressing existential and spiritual distress at end of life. Dyck recounts how figures such as Aldous Huxley and Humphry Osmond framed mescaline and LSD experiences as ways of opening perception, confronting questions of meaning, and potentially easing the psychological burden of dying, and how these ideas drew on Indigenous ritual uses as well as humanist and philosophical concerns. This historical review aims to trace that relationship between psychedelics and dying care, show how early clinical and philosophical discussions coalesced around palliative concerns, and explain why some of those conversations were interrupted by the criminalisation of psychedelics. Dyck sets out to recover the lost or under-examined strands of mid-century thinking about LSD and related compounds and to consider how those antecedents inform contemporary interest in psychedelics for palliative contexts.

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Study Details

References (4)

Papers cited by this study that are also in Blossom

Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance

Griffiths, R. R., Richards, W. A., Mccann, U. et al. · Journal of Psychopharmacology (2006)

Psychedelics

Nichols, D. E. · Pharmacological Reviews (2016)

Psychedelic medicine: a re-emerging therapeutic paradigm

Tupper, K. W., Wood, E., Yensen, R. et al. · Canadian Medical Association Journal (2015)

Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action

Vollenweider, F. X., Vollenweider-Scherpenhuyzen, M. F. I., Bäbler, A. et al. · NeuroReport (1998)

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Beaussant, Y., Tulsky, J., Guérin, B. et al. · Journal of Palliative Medicine (2021)

The ritual use of ayahuasca during treatment of severe physical illnesses: a qualitative study

Maia, L. O., Daldegan-Bueno, D., Tófoli, L.F. · Journal of Psychoactive Drugs (2020)

21 cited

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