5-MeO-DMT for Microdosing

1 paper and 0 clinical trials exploring 5-meo-dmt as a treatment for microdosing.

CompoundTryptamine

5-MeO-DMT

A potent tryptamine psychedelic known for profound mystical experiences, currently under clinical investigation for TRD and anxiety.

Full 5-MeO-DMT profile
IndicationAround 300 million people worldwide are affected by a variety of mental health conditions that microdosing may address.

Microdosing

Microdosing involves the regular consumption of sub-hallucinogenic doses of psychedelics, primarily for cognitive enhancement and emotional wellbeing. Although popularised through anecdotal reports, rigorous scientific evidence on its effects is still limited, pointing to a critical need for further research in this emerging field.

Full Microdosing profile

Academic Research

1 paper
Paywallindividual

Safety and tolerability of multiple sublingual microdoses of 5-MeO-DMT in adults with moderate symptoms of depression and/or anxiety: a randomized, double-blind, placebo-controlled study

This Phase I clinical trial (n=36) of sublingual 5-MeO-DMT (6-12 mg weekly doses over four weeks) in adults with moderate to high anxiety/depression demonstrated good safety and tolerability with no significant adverse events, rapid absorption with peak plasma concentrations at 20 minutes, dose-dependent neurophysiological modulation without full psychedelic effects, and maintenance of normal cognitive and behavioral function.

Published
Journal
Neuropsychopharmacology
Authors
Albarracín, S. G., Bistue Millón, M. B., Bruno, D., Bruno, M. A., Díaz-Dellavalle, P., Diez, P., Feresin, G. E., Garcés, M. A., Kassuha, D. E., Noguera, L., Orosco, L., Ortiz, J. E., Vita, L., Zanino, M.

Clinical Trials

0 trials

No clinical trials have been tagged with both 5-MeO-DMT and Microdosing yet.

Trials are continuously being added as new studies are registered.

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Search all 5-MeO-DMT papers Search all Microdosing trials Full 5-MeO-DMT profile Full Microdosing profile