Effect of Stimulant Drugs on Social Perception

Randomised, double-blind, crossover within-subject design in healthy volunteers comparing placebo, low-dose MDMA (0.75 mg/kg), high-dose MDMA (1.5 mg/kg) and methamphetamine (20 mg).

Primary aim is to characterise the uniquely social or prosocial effects of MDMA versus a prototypical stimulant; outcomes include behavioural social measures and acute subjective and physiological responses.