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Safety and Pharmacokinetics of GH002 in Healthy Volunteers

Not yet recruitingRegisteredCTG

Double-blind, placebo-controlled, randomised single-dose cohorts (n=64 across cohorts A–G) and an open-label multiple-dose cohort (J) investigating safety and serum pharmacokinetics of IV GH002 (5‑MeO‑DMT) in healthy volunteers.

Details

This study evaluates safety and serum pharmacokinetics of GH002 (5‑MeO‑DMT) in healthy volunteers using a randomized, double‑blind, placebo‑controlled single‑dose escalation (cohorts A–G) and an open‑label, non‑randomized multiple‑dose cohort (J).

Secondary objectives include PK/PD relationships, assessment of psychoactive effects and cognitive performance, and measurement of the metabolite bufotenine.

Topics:Healthy Volunteers

Registry

Registry linkNCT05753956