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Current Biology

3 Papers Indexed in Blossom

Published Papers

Open Accessindividual

Whole-brain multimodal neuroimaging model using serotonin receptor maps explains non-linear functional effects of LSD

This neuroimaging model (2018) of the whole brain (under LSD influence) offers causal (and non-linear) mechanisms linking neuromodulation and neuronal activity.

Published
Journal
Current Biology
Authors
Deco, G., Cruzat, J., Cabral, J., Whybrow, P. C., Logothetis, N. K., Kringelbach, M. L., Knudsen, G. M., Carhart-Harris, R. L.
Open Accessindividual

The fabric of meaning and subjective effects in LSD-induced states depend on serotonin 2A receptor activation

This double-blind, placebo-controlled fMRI study (n=22) investigated the neuropharmacology of personal relevance processing by administering LSD with and without the 5-HT2A antagonist ketanserin. Results indicate that ketanserin fully blocked the LSD-induced attribution of meaning to previously meaningless stimuli, suggesting a crucial role for the 5-HT2A receptor in generating personal relevance.

Published
Journal
Current Biology
Authors
Preller, K. H., Herdener, M., Pokorny, T., Liechti, M. E., Seifritz, E., Vollenweider, F. X., Planzer, A., Kraehenmann, R., St€, P.
Open Accessindividual

Increased global functional connectivity correlates with LSD-induced ego dissolution

This seminal fMRI, double-blind, placebo-controlled study (n=15) found that LSD (75µg) increased global connectivity in the brain, which correlated with 'ego dissolution' and which overlapped significantly with where serotonin (5-HT2a) receptors are found.

Published
Journal
Current Biology
Authors
Tagliazucchi, E., Roseman, L., Kaelen, M., Feilding, A., Nutt, D. J., Carhart-Harris, R., Orban, C., Muthukumaraswamy, S. D., Murphy, K., Laufs, H., Leech, R., Mcgonigle, J., Crossley, N., Bullmore, E., Williams, T., Bolstridge, M.

Quick Facts

Papers Indexed
3
h-Index
376
Open Access
No
Publisher
Elsevier
Country
United States
Website
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