Equity and Ethics

Reconciling Mystical Experiences with Naturalistic Psychedelic Science: Reply to Sanders and Zijlmans

This commentary (2021) offers a rebuttal to the opinion piece on Moving Past Mysticism in Psychedelic Science by Sanders and Zijlmans and argues against the notion of demystifying psychedelic experiences or dismissing mystical experiences from the scope of empirical inquiry. Given that all experiences are ineffable by the nature of their subjectivity, it is argued that the epistemic gap between subjective and objective viewpoints of consciousness is a question of philosophy and that it is not the role of science to decide whether metaphysical insights related to mystical experiences are compatible with their particular worldview.

Authors

  • Jylkkä, J.

Published

ACS Pharmacology and Translational Science
individual Study

Abstract

In a recent Viewpoint, Sanders and Zijlmans call for the demystification of psychedelic science. However, they ignore the subjective aspect of psychedelic experiences. For the subject, mystical experiences are felt as real and can yield personally meaningful insights. It is a philosophical question whether they are true.

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Research Summary of 'Reconciling Mystical Experiences with Naturalistic Psychedelic Science: Reply to Sanders and Zijlmans'

Introduction

Sanders and Zijlmans recently argued that psychedelic science should be demystified because concepts such as the mystical experience appear to conflict with a naturalistic, empirical approach. They highlighted that instruments like the Mystical Experience Questionnaire (MEQ-30) probe items such as transcendence of space and time, unity, sacredness and ineffability, and warned that such framing may bias participants and therefore pose both methodological and ethical problems—especially for participants who identify as nonspiritual. Jylkkä replies to that Viewpoint by arguing that the subjective aspect of psychedelic experience deserves philosophical as well as scientific attention. Rather than denying or reducing mystical reports to mere neural events, the author proposes treating metaphysical insights arising in psychedelic states as philosophical intuitions that can be evaluated for truth or falsity. To illustrate this reconciliatory stance, Jylkkä discusses how unitary experiences and panpsychist-type intuitions can be given conceptualisations that are compatible with a scientific worldview.

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Study Details

  • Study Type
    individual
  • Journal
  • Topic
  • APA Citation

    Jylkkä, J. (2021). Reconciling Mystical Experiences with Naturalistic Psychedelic Science: Reply to Sanders and Zijlmans. ACS Pharmacology & Translational Science, 4(4), 1468-1470. https://doi.org/10.1021/acsptsci.1c00137

References (4)

Papers cited by this study that are also in Blossom

Moving Past Mysticism in Psychedelic Science

Sanders, J. W. · ACS Pharmacology and Translational Science (2021)

Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin

Barrett, F. S., Johnson, M. W., Griffiths, R. R. · Journal of Psychopharmacology (2015)

Psychedelic Harm Reduction and Integration: A Transtheoretical Model for Clinical Practice

Palhano-Fontes, F., Gorman, I., Nielson, E. M. et al. · Frontiers in Psychology (2021)

Cited By (4)

Papers in Blossom that reference this study

Transpersonal Ecodelia: Surveying Psychedelically Induced Biophilia

Luke, D., Gandy, S., Irvine, A. et al. · Psychoactives (2023)

17 cited
Psychedelics, Mystical Experience, and Therapeutic Efficacy: A Systematic Review

Knight, G., Rucker, J., Cleare, A. J. et al. · Frontiers in Psychiatry (2022)

Working with Weirdness: A Response to “Moving Past Mysticism in Psychedelic Science”

Breeksema, J. J., van Elk, M. · ACS Pharmacology and Translational Science (2021)

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