151 Organisations

Independent Academic Research Groups

Independent university-based research groups conducting psychedelic science outside large multi-site centres.

All Organisations

Belgium

AZ Delta

Other

AZ Delta is a major Belgian hospital group headquartered in Roeselare, Flanders, operating four campuses with 1,403 approved beds. It participates in the multi-centre BIKe (Brain Injury and Ketamine) randomized controlled trial (NCT05097261) investigating ketamine's safety as an adjunct sedative in severe traumatic brain injury.

1 trial
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Belgium

AZ Sint-Jan AV

Other

AZ Sint-Jan Brugge-Oostende AV is a leading Belgian teaching hospital in Bruges with a dedicated Clinical Trial Center (CTC) that sponsors and participates in academic and commercial drug studies. Its Department of Anesthesiology and Intensive Care Medicine is a confirmed site in the BIKe (Brain Injury and Ketamine) randomized controlled trial (NCT05097261) investigating ketamine's role in severe traumatic brain injury management.

1 trial
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Belgium

AZ Turnhout

Other

AZ Turnhout is a general hospital in Turnhout, Antwerp province, Belgium, providing comprehensive medical and surgical care to the northern Campine region. Its Department of Anesthesiology and Intensive Care Medicine is a confirmed site in the BIKe (Brain Injury and Ketamine) randomized controlled trial (NCT05097261) investigating ketamine as an adjunct sedative in severe traumatic brain injury patients.

1 trial
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France

Assistance Publique - Hôpitaux de Paris

Other

Assistance Publique – Hôpitaux de Paris (AP-HP) is France's largest public hospital system, comprising 39 hospitals including Pitié-Salpêtrière and Sainte-Anne, and serving as Europe's leading academic medical center complex with extensive clinical research infrastructure. AP-HP institutions actively contribute to psychedelic medicine research, including participation in COMPASS Pathways' Phase 3 psilocybin trials for treatment-resistant depression and ketamine studies through the Paris Brain Institute.

2 trials
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France

Assistance Publique Hopitaux De Marseille

Other

Assistance Publique Hôpitaux de Marseille (AP-HM) is the public hospital authority of Marseille, France, comprising four major hospital groups and operating as one of the largest university hospital centers in Europe with extensive clinical research infrastructure. AP-HM has been involved in psychedelic medicine research through its clinical trial network, contributing to France's emerging landscape of psychiatry trials exploring psychedelic-assisted therapies.

1 trial
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United Kingdom

AstraZeneca

Big Pharma

AstraZeneca is a British-Swedish multinational biopharmaceutical company developing medicines across oncology, cardiovascular, respiratory, and neurological areas, with psychiatric products that intersect with psychedelic research contexts. AstraZeneca's antidepressants and psychiatric medications have featured as active comparators in landmark psychedelic clinical trials, including the influential psilocybin vs. escitalopram depression study at Imperial College London.

1 trial
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Australia

Bayside Health

Other

Bayside Health, operating as Alfred Health, is a Melbourne-based public healthcare network comprising The Alfred, Caulfield Hospital, and Sandringham Hospital, and serves as the principal teaching hospital partner for Monash University's Clinical Psychedelic Lab. As host institution for Victoria's major trauma and psychiatric services, it provides clinical infrastructure supporting Australia's psychedelic therapy programmes following the 2023 TGA rescheduling.

1 trial
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Spain

Beckley Med Foundation

Non-Profit

Fundación Beckley Med is a Barcelona-based psychedelic research and education organisation, partnered with the UK's Beckley Foundation, that funds and disseminates psychedelic-assisted therapy studies and provides professional training through institutional affiliations with MAPS, Grof Legacy, and CIIS. It collaborated with CITA Clinic to deliver experimental ketamine treatment to patients with treatment-resistant depression in Spain.

2 trials
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Israel

Beer Yaakov Hospital

Other

Israeli psychiatric hospital near Tel Aviv that served as a key clinical trial site for MAPS-sponsored MDMA-assisted psychotherapy for PTSD, with Dr. Moshe Kotler serving as principal investigator. Beer Yaakov is slated to participate in future MAPS Israel trials treating post-October 7 PTSD among Nova festival survivors and soldiers, in collaboration with the Israeli Ministry of Health.

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China

Beijing Tiantan Hospital

Other

China's premier neurology and neurosurgery hospital, affiliated with Capital Medical University and home to the National Clinical Research Center for Neurological Diseases. Conducted the PASSION trial — a randomized, placebo-controlled study of intraoperative ketamine for depression in neurosurgical patients.

4 trials
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United States

Berkeley University

Other

UC Berkeley Center for the Science of Psychedelics (BCSP), founded in September 2020 by a multidisciplinary faculty group including neuroscientist Michael Silver and author Michael Pollan, conducting psilocybin research into cognition, perception, emotion, and their neural bases in the human brain. BCSP's four pillars of basic science, journalism, culture, and community have established it as a leading interdisciplinary hub for psychedelic research and public engagement, producing The Microdose newsletter and a global clinical trials map.

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United States

Berry Consultants

Other

Berry Consultants is a US statistical consulting firm specializing in Bayesian adaptive clinical trial design, with expertise in platform trials and adaptive dose-finding studies increasingly applied in psychedelic and psychiatric drug development. The firm has engaged with regulatory frameworks for psychedelic medicines, including commenting on FDA guidance for clinical trials involving psilocybin and MDMA.

1 trial
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Denmark

Bispebjerg Hospital

Other

Bispebjerg Hospital is a major Copenhagen university hospital and the coordinating site for PsyPal, the EU-funded multi-centre trial investigating psilocybin-assisted therapy for anxiety and existential distress in patients with ALS—the first European publicly-funded psychedelic trial of its kind. Affiliated with the University of Copenhagen, the hospital leads Nordic clinical research into psychedelic-assisted therapies for neurological and palliative conditions.

1 trial
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Canada

Braxia Scientific Corp.

Public Biotech

Braxia Scientific Corp. (CSE: BRAX) is a Canadian publicly-listed medical research company that operates a network of ketamine and psilocybin treatment clinics across Ontario and Quebec through its subsidiary Canadian Rapid Treatment Centre of Excellence, and conducted Canada's first multi-dose Phase II psilocybin randomized controlled trial for treatment-resistant depression. The company received Health Canada Special Access Program approval to deliver psilocybin-assisted therapy in Ontario and holds government-funded grants for ketamine trials in bipolar depression, led by researchers Dr. Roger McIntyre and Dr. Joshua Rosenblat.

1 trial
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United States

Brigham and Women's Hospital

Other

Major academic medical center in Boston affiliated with Harvard Medical School and part of the Mass General Brigham health system. Researchers at BWH are active in the emerging field of psychedelic-assisted therapy, including psilocybin studies for gastrointestinal conditions and ethical frameworks for psychedelic pain research.

5 trials
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United States

Bronx Veterans Medical Research Foundation

Non-Profit

The Bronx Veterans Medical Research Foundation (BVMRF) is a 501(c)(3) nonprofit that administers extramural research funding for the James J. Peters VA Medical Center and VA Hudson Valley Health Care System, supporting mental health, biomedical, and rehabilitation research focused on veteran populations. In the psychedelic context, it provides the administrative research infrastructure supporting MDMA-assisted therapy for PTSD and ketamine studies conducted at the Bronx VA's Center for Psychedelic Psychotherapy and Trauma Research.

1 trial
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Canada

Bruyère Health Research Institute.

Non-Profit

Bruyère Health Research Institute is the academic research arm of Bruyère Health in Ottawa, Canada, fully affiliated with the University of Ottawa and specializing in palliative care, aging, and rehabilitation research—areas with growing overlap with psychedelic-assisted therapy applications. The institute contributed to a major Ontario population study examining schizophrenia risk following hallucinogen-related emergency department visits, generating safety evidence informing screening protocols for psychedelic clinical trials.

2 trials
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United States

CH TAC LLC

Non-Profit

CH TAC LLC (Cluster Headache-Trigeminal Autonomic Cephalalgia, LLC) is a US non-profit research entity that co-sponsored Yale University's Phase 1 psilocybin trials for episodic and chronic cluster headache, in partnership with Heffter Research Institute and Ceruvia Lifesciences.

1 trial
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United States

CUIMC

Other

Columbia University Irving Medical Center (CUIMC) is a major academic medical centre in New York City, integrating Columbia University's Vagelos College of Physicians and Surgeons with NewYork-Presbyterian Hospital and conducting research across neuroscience, psychiatry, and translational medicine. CUIMC serves as the primary clinical site for the Ketamine Biomarker Validation trial (NCT07307768), an EEG-based Phase I study examining dose-response relationships across three ketamine infusion levels in adults with treatment-resistant major depressive disorder.

1 trial
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United Kingdom

Cambridge Cognition Ltd

Public Biotech

Cambridge Cognition (AIM: COG) is a UK-based cognitive technology company that develops and licenses the CANTAB neuropsychological assessment platform, validated in over 3,000 publications and widely adopted in psychedelic clinical trials—including psilocybin and MDMA studies—to objectively measure cognitive outcomes at baseline, during, and after treatment. CANTAB’s digital cognitive assessments have become a de facto standard endpoint tool in psychiatric drug development, supporting the field’s progression through Phase 2 and Phase 3 psychedelic trials.

1 trial
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Netherlands

Canisius-Wilhelmina Hospital

Other

Canisius-Wilhelmina Hospital (CWZ) is a major teaching hospital in Nijmegen, Netherlands, whose Department of Neurology has contributed to psychedelic research including an evidence-based review of LSD and psilocybin for chronic pain management, examining serotonin-2A receptor-mediated neuroplastic mechanisms. Situated in the Netherlands—one of Europe’s most active countries for psychedelic research—CWZ participates in neurological research exploring psychedelic compounds as therapeutic agents for pain and psychiatric conditions.

1 trial
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United States

Center for Medicinal Cannabis Research

Other

The Center for Medicinal Cannabis Research (CMCR) is a California state-funded research program at UC San Diego that rigorously evaluates the medical efficacy and safety of cannabis and cannabinoids through placebo-controlled clinical trials, with regulatory expertise in Schedule I research that overlaps with psychedelic medicine. CMCR has been cited in psychedelic trial contexts for its methodological framework and experience navigating DEA/FDA processes for controlled-substance clinical research applicable to psilocybin and MDMA studies.

1 trial
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Germany

Central Institute of Mental Health, Mannheim

Other

The Central Institute of Mental Health (ZI Mannheim) is a leading German psychiatric research institute affiliated with Heidelberg University, and under Prof. Dr. Gerhard Gründer is one of Europe’s foremost centers for psychedelic research—co-leading EPIsoDE, Germany’s first federal government-funded (BMBF, €2.2M) Phase II RCT of psilocybin for treatment-resistant depression, and receiving one of the first compassionate-use approvals for psilocybin in Germany and the EU, with results published in Lancet Psychiatry in 2025. The institute also conducts molecular neuroimaging research on MDMA and psilocybin mechanisms, and has reported successful ketamine treatment outcomes in treatment-resistant depression.

1 trial2 papers
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Netherlands

Centre for Human Drug Research, Netherlands

Other

The Centre for Human Drug Research (CHDR) in Leiden, Netherlands is a world-class early-phase clinical research organization conducting approximately 60 trials per year, with a specialist psychiatry department that has become one of Europe’s leading sites for psychedelic compound research—including psilocybin, DMT, MDMA, and ketamine—using advanced tools such as the NeuroCart CNS battery and EEG to quantify pharmacodynamic endpoints. CHDR has conducted first-in-human studies with novel non-hallucinogenic neuroplastogens and intravenous DMT regimens, establishing it as a key early-phase partner for psychedelic drug development.

1 trial
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Canada

Centre for Neurology Studies, Canada

Other

The Centre for Neurology Studies (CNS) is a private clinical research centre in Surrey, British Columbia, and one of Canada’s few dedicated neuroscience-focused clinical trial organizations, conducting Health Canada and FDA-approved studies in mental health, neurodegenerative disorders, and brain health. Operating within British Columbia’s growing clinical trials ecosystem, CNS has participated in research on novel psychiatric treatments relevant to the emerging psychedelic medicine field.

1 trial
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Denmark

Cessatech A/S

Public Biotech

Cessatech A/S is a Copenhagen-based paediatric biotech developing CT001, a first-in-class intranasal ketamine/sufentanil combination analgesic for acute pain in children aged 1–17, with an EMA Marketing Authorisation Application submitted in 2025 and approval expected in 2026.

1 trial
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Germany

Charité – Universitätsmedizin Berlin

The MIND Foundation partnered with Charité – Universitätsmedizin Berlin, one of Europe's largest university hospitals. Charité is affiliated with Humboldt University and Free University Berlin. This partnership sees researchers at the hospital carrying out clinical studies with psilocybin in patients with treatment-resistant depression. Studies also take place concurrently at the Central Institute for Mental Health Mannheim.

1 trial1 paper
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Canada

Children's Hospital of Eastern Ontario

Other

The Children’s Hospital of Eastern Ontario (CHEO) is a leading Canadian pediatric tertiary care hospital in Ottawa affiliated with the University of Ottawa; CHEO Research Institute supports over 250 researchers, and CHEO is conducting a clinical trial of IV ketamine for suicidal ideation in youth.

1 trial
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Switzerland

Cy Biopharma

Private Biotech

Cy Biopharma AG is a Swiss biotech company developing novel psilocybin-derived small molecule therapies for chronic pain and other CNS conditions, with a focus on rare and orphan indications. Operating from Baar, Switzerland, Cy screens biochemical extracts combined with serotonin receptor agonists to create new molecular entities, and has formed a strategic supply and collaboration partnership with Australian life sciences company Bioxyne Limited for Australasia and global markets.

1 trial
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United Kingdom

Drug Science

Drug Science is a UK-based independent scientific body that supports evidence-led drug policy and public education, and has played a visible role in psychedelic research translation, communication, and policy discourse.

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United States

ERT: Clinical Trial Technology Solutions

Other

Clinical trial technology provider (now part of Clario branding) offering neuroscience-focused eCOA and endpoint-quality services for global CNS studies, including methodologies relevant to psychedelic-assisted therapy trials.

1 trial
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Canada

Ehave Inc.

Other

Ehave Inc. is a Canadian digital health company providing telemetry and data-collection platforms for precision-medicine clinical trials, including psychedelic and ketamine research; their KetaDASH product enables ketamine home-delivery monitoring for medical practitioners. The company holds an FDA-authorized IND for a ketamine EEG study in major depressive disorder.

1 trial
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United States

EmpathBio, Inc.

Subsidiary

EmpathBio Inc. is an ATAI Life Sciences subsidiary developing EMP-01, an MDMA derivative designed to preserve entactogenic therapeutic properties while reducing cardiovascular and stimulant side effects, with PTSD as the primary indication. The company completed a Phase 1 trial of EMP-01 in 32 healthy volunteers in New Zealand.

1 trial
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Canada

Empower Research Inc

Non-Profit

Empower Research Inc. is the corporate research entity behind Empower Psychedelics, running Health Canada-approved trials on psychedelic-assisted group therapy for first responders in partnership with MAPS Canada. The organization has also studied medically perceived benefits of psychedelics and cannabinoids among first responders and military personnel.

2 trials
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Italy

European Association for Palliative Care (EAPC)

Non-Profit

The European Association for Palliative Care (EAPC) is the leading European professional body for palliative care research, education, and policy, headquartered in Milan. The EAPC is a core consortium partner in PsyPal, the first EU-funded multi-site psilocybin clinical trial (€6.5M), studying psilocybin-assisted therapy for psychological distress in patients with COPD, MS, ALS, and atypical Parkinson's disease across multiple European sites.

1 trial
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FHNW

The University of Applied Sciences and Arts Northwestern Switzerland (FHNW) is a public Swiss university of applied sciences offering practice‑oriented bachelor’s and master’s programs across multiple schools (engineering, business, life sciences, art & design, education, etc.) and conducting applied research, continuing education, and regional services.

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Canada

Field Trip Health

Public Biotech

Field Trip Health was a Canadian publicly traded ketamine-assisted psychotherapy company founded in 2019 that operated clinics across North America and Europe while developing FT-104, a shorter-duration psilocybin analog, before a 2023 financial restructuring under Canada's Companies' Creditors Arrangement Act. Its drug development assets were spun off as Reunion Neuroscience (which raised $103M Series A in 2024) while its US clinic network was acquired by Stella and its Canadian clinics by the Canadian Centre for Psychedelic Healing.

1 trial
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United States

Florida International University

Other

Miami public research university where Dr. Jerry B. Brown has taught interdisciplinary psychedelics courses since 1975, and Professor Joseph Lichter runs an Honors College Psychedelic Renaissance course covering therapeutic applications of psilocybin, MDMA, and ketamine. FIU also serves as one of 21 sites in a major national psychedelic clinical trial and hosts the Cannadelic conference — the first cannabis and psychedelics conference focused on next-generation research.

1 trial
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Netherlands

Free University Amsterdam

Other

Vrije Universiteit Amsterdam (VU Amsterdam) is a major Dutch research university where neuroscientist Marco Aqil conducted the first psilocybin brain research in Amsterdam, demonstrating that psilocybin fundamentally alters visual processing by reducing cortical surround suppression. The university also hosts the Amsterdam Psychedelic Research Association (APRA) and offers an interdisciplinary honors course on the neuroscience, history, and therapeutic potential of psychedelics.

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Spain

Germans Trias i Pujol Hospital

Other

Hospital Universitari Germans Trias i Pujol is a major public academic hospital in Badalona, Catalonia, Spain, whose Clinical Pharmacology Unit led by Dr. Magí Farré has conducted extensive human pharmacology studies on MDMA, 2C-B, and other psychedelics. The hospital's ethics committee approved the Beckley Med Foundation's ayahuasca-assisted therapy trial for complicated grief (NCT06150859), and its research institute (IGTP) lists the therapeutic use of psychedelic substances as an active research area.

1 trial1 paper
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Belgium

Grand Hôpital de Charleroi

Non-Profit

Grand Hôpital de Charleroi (GHdC) is a large multi-site hospital system with six hospitals in Charleroi, Wallonia, Belgium, listed as a clinical research center on the European Clinical Trials Information Network. The hospital sponsors ESKEFIB (NCT04436250), a prospective randomized double-blind trial evaluating S-ketamine as a treatment for fibromyalgia, contributing to Belgium's growing ketamine clinical research infrastructure.

1 trial
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United States

HHC Research Open Competition

Non-Profit

The Hartford HealthCare (HHC) Research Open Competition is an internal pilot grant program run by Hartford HealthCare — a large non-profit integrated health system in Connecticut — to fund investigator-initiated research at its affiliated institutions. Through this program, HHC supports a Phase I double-blind psilocybin microdosing trial at its Olin Neuropsychiatry Research Center in Hartford, investigating effects on cognition, mood and quality of life.

1 trial
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Israel

Hadassah Medical Organization

Non-Profit

Hadassah Medical Organization is a major non-profit academic medical center in Jerusalem, Israel, home to the Hadassah BrainLabs Center for Psychedelic Research, which develops novel psychedelic-based treatments for psychiatric disorders. The organization runs MDMA-assisted psychotherapy trials for PTSD (NCT06954025) and ketamine trials for depression (NCT05026203), and serves as the Phase 1 clinical pharmacology site for Ketamir-2, a novel oral ketamine analog.

3 trials
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United Kingdom

Hammersmith Medicines Research

Other

Hammersmith Medicines Research (HMR) is the UK's largest Phase 1 clinical research organization, holding MHRA Phase 1 accreditation and a Home Office licence for controlled drug substances including psychedelics. HMR led the Phase I/IIa clinical trial of SPL026 (DMT fumarate) for major depressive disorder on behalf of Small Pharma, positioning it as a leading UK site for early-phase psychedelic medicine trials.

1 trial
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United States

Harvard University

Non-Profit

Harvard University hosts multiple psychedelic research initiatives including the Study of Psychedelics in Society and Culture (a $16M program), the MGH Center for the Neuroscience of Psychedelics, and the Harvard Law School POPLAR project addressing psychedelic policy reform. These programs span neuroscience, cultural studies, and legal advocacy to advance scientific and societal understanding of psychedelics.

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China

Henan Provincial People's Hospital

Other

Henan Provincial People's Hospital is a major 3A-grade hospital in Zhengzhou, China, with over 4,000 beds and a history dating to 1904; it is a key academic medical center affiliated with Zhengzhou University. Its anesthesiology department researches esketamine applications, including a trial on reducing postoperative anxiety and depression in adolescent patients.

2 trials
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United States

Henry M. Jackson Foundation for the Advancement of Military Medicine

Non-Profit

The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a congressionally chartered non-profit founded in 1983 that manages research contracts and grants for the U.S. Department of Defense across global health, HIV, TBI, and PTSD. HJF is affiliated with clinical research investigating ketamine for sedation in severe traumatic brain injury — a condition at the intersection of military medicine and emerging ketamine-based therapies.

1 trial
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Israel

Herzog Hospital

Non-Profit

Herzog Hospital is Israel's oldest psychiatric institution (est. 1894), operating 550 beds in Jerusalem and home to the country's only dedicated inpatient unit for severe treatment-resistant depression. Researcher Dr. Uriel Heresco-Levy leads investigation of novel psilocybin combinations with NMDAR modulators for depression, including a joint patent with Hadassah BrainLabs (PCT WO 2024/052895 A1).

1 trial
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United States

Homeostasis Therapeutics, LLC

Private Biotech

Homeostasis Therapeutics LLC is a Delaware company (est. 2020) that developed a novel protocol combining medically supervised ketogenic diet with ketamine infusions for treatment-resistant anorexia nervosa. In 2021–2022 they conducted a five-person IRB-approved pilot study in which four of five participants showed meaningful clinical improvement, advancing the concept of metabolic-state-dependent psychedelic therapy.

1 trial
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Argentina

Hospital Descentralizado Dr. Marcial V. Quiroga

Other

Hospital Descentralizado Dr. Marcial V. Quiroga is a public hospital in Rivadavia, San Juan Province, Argentina, serving as a key healthcare facility for the Cuyo region with active research and teaching programs. The hospital is a site for pioneering trials of sublingual 5-MeO-DMT — investigating microdoses for depression and anxiety, and higher doses for anxiety and depression in mild cognitive impairment — among the first Argentine institutions to participate in 5-MeO-DMT clinical research.

2 trials
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Brazil

Hospital Moinhos de Vento

Other

Hospital Moinhos de Vento (HMV) is a leading private non-profit hospital in Porto Alegre, Brazil, recognized as one of the country’s top healthcare institutions by national quality rankings. HMV is a reference center for ketamine treatment and co-hosts a naturalistic multicenter study (NCT05249309) with HCPA on subcutaneous ketamine infusions for depressed patients with active suicidal ideation.

1 trial
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Spain

Hospital Universitari Sant Joan de Reus

Other

Hospital Universitari Sant Joan de Reus is a Catalan university hospital operated by Grup SAGESSA in Reus, Tarragona, with a pioneering harm reduction and substance use disorders program. In 2020, ICEERS partnered with the hospital to conduct the first-ever Phase II clinical trial of ibogaine for opioid-dependent patients on methadone maintenance, making Sant Joan one of Europe’s most historically significant psychedelic research sites.

1 trial
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Brazil

Hospital de Clinicas de Porto Alegre

Other

Hospital de Clínicas de Porto Alegre (HCPA) is a major university hospital affiliated with the Universidade Federal do Rio Grande do Sul (UFRGS) and one of Brazil’s leading academic medical centers. HCPA researchers conduct active ketamine research, including a study of ketamine combined with electroconvulsive therapy for depression and a multicenter trial of subcutaneous ketamine infusions for patients with active suicidal ideation (NCT05249309).

2 trials
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Sweden

HumanKindLabs

Non-Profit

Platform organization developing and supporting psychedelic and mental-health initiatives with philanthropic backing.

1 trial
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China

Hunan Provincial Maternal and Child Health Care Hospital

Other

Hunan Provincial Maternal and Child Health Care Hospital is a Class-III Grade-A specialist maternity and pediatric hospital in Changsha, Hunan Province, China, founded in 1947 with over 1,050 beds and 10,000 births annually. The hospital’s anesthesiology team is a leader in esketamine obstetrics research, including a landmark BMJ randomised trial (NCT04414943) showing a single low-dose esketamine infusion after childbirth reduced major postpartum depression at 42 days by approximately three-quarters in mothers with prenatal depression.

2 trials
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Spain

IESE Business School

Non-Profit

IESE Business School is a global graduate business school at the University of Navarra, based in Barcelona, that contributes to psychedelic research through the PsyPal consortium. As part of the first EU-funded psychedelic clinical study (€6.5M, 19 partners), IESE hosts design thinking workshops and brings expertise in health economics, organizational implementation, and stakeholder strategy to support the psilocybin palliative care trial.

1 trial
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Switzerland

Idorsia Pharmaceuticals Ltd.

Public Biotech

Idorsia Pharmaceuticals Ltd. is a Swiss publicly traded biopharmaceutical company (spun out of Actelion in 2017) focused on developing medicines for high-unmet-need conditions, with products including the dual orexin receptor antagonist daridorexant (Quviviq) for insomnia. Idorsia is a participating organization in the U.S. Department of Defense PTSD Adaptive Platform Trial, which evaluates multiple therapeutic interventions — including the intranasal ketamine compound SLS-002 — for veterans with treatment-resistant PTSD.

1 trial
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Belgium

Imelda Hospital, Bonheiden

Non-Profit

Imelda Hospital is a Catholic general hospital in Bonheiden, in the Antwerp province of Belgium, offering a full range of acute care and specialist services across approximately 550 beds. The hospital has contributed to clinical research on ketamine for the management of acute brain injury patients.

1 trial
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United States

Inc.

Other

This stakeholder record appears to be a data parsing artifact where only the corporate suffix 'Inc.' was captured without the full organization name. It is listed as a collaborator in two US psilocybin research trials: a VA-sponsored Phase I/II study on psilocybin for depression in spinal cord injury veterans (NCT07251491) and a group retreat psilocybin therapy trial for cancer patients at Fred Hutch/UW Cancer Consortium (NCT07336238).

2 trials
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United States

Institute for Integration of Medicine & Science-UT Health San Antonio

Other

The Institute for Integration of Medicine & Science (IIMS) at UT Health San Antonio is the institution's NIH-funded Clinical and Translational Science Award hub, supporting multi-disciplinary translational research across South Texas. The institute has been involved in a clinical trial combining esketamine with prolonged exposure therapy for post-traumatic stress disorder.

1 trial
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Mexico

Instituto Nacional de Cancerologia de Mexico

Other

Instituto Nacional de Canciología de México (INCan) is Mexico's federal national cancer institute in Mexico City, operating as a leading oncology specialty hospital and research center. The institute has participated in a clinical trial examining ketamine versus placebo for treating major depression in patients with advanced cancer.

1 trial
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Instituto do Cérebro, Universidade Federal do Rio Grande do Norte

The Instituto do Cérebro (Brain Institute, ICe) is an academic research institute of the Federal University of Rio Grande do Norte (UFRN) in Natal, Brazil, focused on neuroscience research, education and public outreach. It hosts the postgraduate Program in Neurosciences (PGNeuro) and supports related research groups and events.

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Turkey

Istanbul Training and Research Hospital

Other

Istanbul Training and Research Hospital is a major public academic medical center in Istanbul, Turkey, affiliated with the Istanbul Provincial Health Directorate and serving as a regional training hub for medical residents and specialists across multiple disciplines. The hospital has conducted clinical research on subanesthetic ketamine doses for postoperative mood improvement in gynecological surgical patients.

1 trial
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Italy

Istituto Superiore di Sanità

Other

Istituto Superiore di Sanità (ISS) is Italy's National Institute of Health, the country's principal technical and scientific public body for biomedical research, public health surveillance, and regulatory advisory functions. The institute has participated in pharmacological research on designer psychoactive substances including methylone, an MDMA analogue, contributing to Italy's evidence base for novel psychoactive substance regulation.

1 trial
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South Korea

Janssen Korea, Ltd., Korea

Subsidiary

Janssen Korea Ltd. is the South Korean affiliate of Janssen Pharmaceuticals, the pharmaceutical subsidiary of Johnson & Johnson. The company markets esketamine nasal spray (Spravato) in South Korea following regulatory approval for treatment-resistant depression and major depressive disorder with acute suicidal ideation.

1 trial
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China

Jiangsu HengRui Medicine Co., Ltd.

Public Biotech

Jiangsu HengRui Medicine Co., Ltd. is one of China's largest publicly listed pharmaceutical companies, specializing in innovative drugs across oncology, anesthesia, and metabolic diseases. The company has developed HR071603, a proprietary ketamine nasal spray candidate, which entered Phase I clinical evaluation in healthy subjects.

1 trial
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Johns Hopkins Center for Psychedelic and Consciousness Research

A research center within Johns Hopkins University (School of Medicine) that conducts scientific studies on psychedelic compounds, their effects on brain function and consciousness, and their therapeutic potential for mental health conditions.

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United States

Johnson & Johnson

Big Pharma

Johnson & Johnson is tracked as an institutional-capital stakeholder relevant to financing exposure in psychedelic and adjacent mental-health sectors.

2 trials
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United States

Juvenile Bipolar Research Foundation

Non-Profit

The Juvenile Bipolar Research Foundation is a US non-profit dedicated to funding scientific research into bipolar disorder in children and adolescents. The foundation has supported clinical research on intranasal ketamine for pediatric bipolar disorder and neurobiological studies of ketamine's effects in children and adults with bipolar disorder.

2 trials
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Canada

KGK Science Inc.

Other

KGK Science Inc. is a Canadian contract research organization (CRO) based in London, Ontario, specializing in clinical trial execution across natural health products, novel therapeutics, and medical devices. The company has served as a trial management partner on psilocybin studies for treatment-resistant PTSD and behavioral and cognitive symptoms in adults with Fragile X Syndrome.

2 trials
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Sweden

Karolinska Institutet

Other

Karolinska Institutet is Sweden's largest medical university and a leading European hub for psychedelic research, with the Centre for Psychiatry Research led by Prof. Johan Lundberg conducting PSIPET — Sweden's first RCT of psilocybin for major depressive disorder. The institute participates in the Nordic Network for Psychedelic Science and launched a doctoral course in psychedelic science in 2025.

2 trials
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United States

Kernel

Private Biotech

Neurotechnology company developing non-invasive brain measurement systems with applications in psychiatry and published psychedelic-adjacent ketamine research collaborations.

1 trial
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United States

Klarisana Physician Services PLLC

Other

One of the longest-operating ketamine therapy networks in the United States, Klarisana runs five intramuscular ketamine clinics across Texas and Colorado—founded in San Antonio in 2015 and a founding member of the American Society of Ketamine Physicians. The practice participated in clinical research on ketamine infusion therapy for PTSD in paramedics, having administered nearly 20,000 IM ketamine sessions annually by 2022.

1 trial
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United States

Kures, Inc.

Subsidiary

An atai Life Sciences subsidiary and Columbia University spinout, Kures developed KUR-101—a deuterated mitragynine derivative from the kratom plant—as a safer opioid receptor modulator for acute pain and opioid use disorder, with a second asset KUR-002 targeting depression. The Phase 1 trial of KUR-101 in healthy adults demonstrated safety and tolerability with no severe adverse events, advancing a kratom-derived mechanism distinct from conventional opioids.

1 trial
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United States

Limbic Medical

Other

A Los Angeles ketamine treatment and functional medicine clinic that pioneered at-home sublingual ketamine microdosing programs, Limbic Medical published research in the Journal of Psychedelic Studies showing 100% improvement in anxiety and 96% improvement in PTSD among frontline healthcare workers treated with daily low-dose sublingual ketamine during the COVID-19 pandemic. The clinic integrates ketamine infusions, hydration therapies, and telemedicine-based microdose programs under its founding physician.

1 trial
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United Kingdom

MAC Clinical Research

Other

UK clinical research organization and site operator focused on complex CNS and psychedelic studies, with dedicated psychedelic testing suites and early-to-late phase delivery capabilities.

1 trial
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Netherlands

MAPS Europe B.V.

Non-Profit

The Amsterdam-based European subsidiary of MAPS (Multidisciplinary Association for Psychedelic Studies), MAPS Europe B.V. was established in 2018 to advance MDMA-assisted psychotherapy through EMA-regulated Phase 2 and Phase 3 clinical trials for PTSD across Europe. The organization ran the first multi-site European MDMA/PTSD Phase 2 open-label study with sites in London, Berlin, Lisbon, and others, and trained therapists from 14 countries.

1 trial
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Germany

MIND Foundation

Non-Profit

European nonprofit research and implementation organization that organizes the INSIGHT Conference and allied public/professional events.

1 trial1 paper
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Netherlands

Maastricht University

While Maastricht University may not have a single dedicated psychedelic research group, various researchers at the university are investigating the effects of psychedelics. Early research exploring psychedelics at Maastricht focused on the dangers of MDMA. Now, research into the effects of microdosing is being led by Dr Kim Kuypers. Other research ongoing at the university is investigating cannabis as well as novel psychoactive substances (NPS). Maastricht is collaborating on research with the Beckley Foundation as well as Silo Pharma.

7 trials4 papers
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France

Madopa

Non-Profit

MADoPA (Maintien en Autonomie à Domicile des Personnes Âgées) is a French expert centre and Living Lab founded in 2008 in Troyes, specializing in the co-design and socio-anthropological evaluation of technologies and services supporting elderly and disabled people’s independence at home, affiliated with EIT Health since 2014. As a PsyPal consortium partner, MADoPA leads the Public and Patient Involvement Workgroup (WP4), contributing qualitative research and ethnographic methodologies to the EU-funded €6.5M psilocybin palliative care trial.

1 trial
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United States

Mayo Clinic

Other

Multi-campus academic medical center and one of the most recognized healthcare institutions in the world. Mayo Clinic researchers have published evidence reviews on psilocybin-assisted therapy for depression, anxiety, and alcohol use disorder, and have collaborated on ketamine clinical trials — including a biomarker study with the University of Michigan — for treatment-resistant depression.

8 trials1 paper
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United States

Mclean Hospital

Other

Harvard Medical School-affiliated psychiatric hospital and one of the leading mental health research institutions in the United States. Operates a dedicated Ketamine Service for treatment-resistant depression and is actively expanding into psilocybin research for depression, bipolar disorder, and other psychiatric conditions.

4 trials
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Medical School Hannover (MHH)

Hannover Medical School (Medizinische Hochschule Hannover, MHH) is a research-intensive university medical centre and teaching hospital located in Hannover, Germany. It provides medical and dental education, conducts clinical and biomedical research (notably in transplantation, infection/immunity and biomedical technology), and operates a large university hospital.

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United States

Melt Pharmaceuticals

Subsidiary

Melt Pharmaceuticals is a US specialty pharmaceutical company — carved out from Harrow, Inc. in 2019 and subsequently re-acquired — that developed MELT-300, a sublingual fast-dissolving tablet combining ketamine (50 mg) and midazolam (3 mg) for opioid-free procedural sedation using Catalent's Zydis® technology. The company reported positive Phase 3 topline results for cataract surgery sedation in November 2024, positioning MELT-300 for FDA regulatory submission.

1 trial
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United States

Mike O'Callaghan Military Hospital

Other

Mike O'Callaghan Military Medical Center is the primary military hospital at Nellis Air Force Base in Las Vegas, Nevada, operated by the 99th Medical Group and serving active duty personnel and their families through TRICARE. The center sponsored the CHECK Trial — a multicenter, randomized, double-blind study comparing sub-dissociative ketamine against prochlorperazine for emergency department headache treatment, published in Annals of Emergency Medicine in 2018.

1 trial
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United Kingdom

NHS Grampian

Other

NHS Grampian is the National Health Service health board serving northeast Scotland — including the city of Aberdeen and surrounding Aberdeenshire — providing acute hospital care through facilities such as Royal Cornhill Hospital and Aberdeen Royal Infirmary. The organisation led the KANECT randomised controlled trial comparing ketamine against propofol as ECT anaesthetic for major depression, conducted at Royal Cornhill Hospital between 2011 and 2013 and published in the British Journal of Psychiatry in 2017.

1 trial
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United States

NWTraumatherapies

Other

NWTraumatherapies is a Bozeman, Montana-based network organisation directed by mechanotherapist Ross Allison that developed the Northwest Therapies Trauma Psilocybin Study (NWTTPS), a compassionate use protocol exploring enhanced psilocybin microdosing for chronic trauma conditions including PTSD, depression, and long COVID. The study (NCT05042466) lists Imperial College London, the WHO, and Johns Hopkins University as scientific collaborators and employs a multi-week microdosing protocol with therapist-supervised integration.

1 trial
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NYU Center for Psychedelic Medicine

NYU Langone Health’s Center for Psychedelic Medicine (NYU CPM) conducts health-focused translational research, education, and training on the therapeutic use of psychedelic drugs across psychiatry, medicine, and preclinical science. It supports clinical trials and a research training program to develop investigators and clinicians in the field.

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United States

NYU Langone Health

Other

Home to the NYU Langone Center for Psychedelic Medicine, one of the world's leading academic institutions in psychedelic research. Has conducted landmark psilocybin trials for smoking cessation, alcohol use disorder, and depression in cancer patients, spearheaded by Dr. Michael Bogenschutz and colleagues.

10 trials
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United States

Nationwide Children's Hospital

Other

Nationwide Children's Hospital is a leading pediatric academic medical center in Columbus, Ohio, operating one of the largest sickle cell disease programs in the state and providing comprehensive care for pediatric hematology, psychiatry, and pain management. The hospital has conducted research on IV ketamine as an adjunct for sickle cell vaso-occlusive pain crises and suicidal ideation in adolescents.

2 trials
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United States

NeuroRx, Inc.

Public Biotech

NRx Pharmaceuticals (formerly NeuroRx, Nasdaq: NRXP) is a clinical-stage biopharmaceutical company developing a sequential therapy for suicidal bipolar depression: NRX-100 (preservative-free IV ketamine) for acute stabilization followed by NRX-101 (D-cycloserine/lurasidone) for maintenance, both holding FDA Breakthrough Therapy Designation. The company filed an NDA with the FDA for NRX-100 in 2024 in support of accelerated approval.

3 trials
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United States

Neurological Associates of West Los Angeles

Other

Neurological Associates of West Los Angeles (NAOWLA) is a private neurology and psychiatry group practice in Santa Monica, California, founded in 1981 and affiliated with the UCLA Department of Neurology. The practice sponsored NCT04205890, a clinical trial investigating intravenous ketamine effects on functional neuroanatomy in treatment-resistant depression via pre/post brain imaging.

1 trial
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United States

New York State Psychiatric Institute

Other

State-funded psychiatric research institute affiliated with Columbia University, located in New York City. A key site for psilocybin clinical trials including the landmark COMP360 study for treatment-resistant depression, and conducts broader research on LSD, DMT, ayahuasca, and ketamine through Columbia's Depression Evaluation Service.

11 trials
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United States

Northwell Health

Other

Northwell Health is New York's largest health system with 28 hospitals, which opened the Center for Psychedelics Research and Treatment (CPRT) at Zucker Hillside Hospital in 2026 to study psilocybin for anxiety disorders, MDMA for schizophrenia negative symptoms, and ketamine for treatment-resistant depression. The center's Feinstein Family Human Neuropsychopharmacology Laboratory is one of only a handful of US facilities licensed to dispense federal Schedule I substances for research.

2 trials
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Switzerland

Novartis Pharmaceuticals

Big Pharma

Novartis is a Swiss multinational pharmaceutical company headquartered in Basel that has advanced MIJ821 — a selective GluN2B/NR2B NMDA receptor antagonist — through a Phase 2 proof-of-concept trial for treatment-resistant depression, exploring the same ketamine-like NMDA antagonism pathway. MIJ821's rapid-acting antidepressant mechanism is part of Novartis's broader CNS drug discovery pipeline.

1 trial
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United States

PPD Development, LP

Other

PPD Development (now part of Thermo Fisher Scientific's clinical research business) is one of the world's largest contract research organizations (CROs), providing trial management and bioanalytical services for clinical programs including DoD-sponsored studies on SLS-002 (intranasal racemic ketamine) for PTSD in military personnel and veterans through the M-PACT adaptive platform trial.

1 trial
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Spain

Parc de Salut Mar

Other

Parc de Salut Mar is a public hospital consortium in Barcelona, Spain, whose research arm IMIM (Hospital del Mar Medical Research Institute) has conducted controlled human pharmacology studies of MDMA and novel psychoactive substances. Their Integrative Pharmacology and Systems Neuroscience Research Group ran landmark double-blind crossover trials comparing mephedrone to MDMA in healthy volunteers and investigating MDMA pharmacokinetics by sex and CYP2D6 genotype.

2 trials
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United States

Perception Neuroscience

Subsidiary

Perception Neuroscience is a New York–based biopharmaceutical subsidiary of atai Life Sciences developing PCN-101 (arketamine, R-ketamine) as a potentially safer, lower-dissociation alternative to racemic ketamine for treatment-resistant depression. The company completed a Phase 1 single-ascending-dose study in 58 healthy volunteers and a Phase 2a double-blind, placebo-controlled trial in TRD patients, with a collaboration with Otsuka Pharmaceutical for the Japanese market.

2 trials
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Canada

Peter Boris Centre for Addictions Research (PBCAR)

Other

The Peter Boris Centre for Addictions Research (PBCAR) is a joint addiction research centre of McMaster University and St. Joseph's Healthcare Hamilton in Canada, directed by Dr. James MacKillop. PBCAR is conducting a Phase 2 clinical trial of psilocybin-assisted psychotherapy — two 25 mg psilocybin sessions combined with an 8-week Motivational Enhancement Therapy program — for cannabis use disorder.

1 trial
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United States

Pfizer

Big Pharma

Pfizer is a multinational pharmaceutical corporation that, through Pfizer Canada and the Canadian Pain Society, co-funded the KetHead multi-center Phase 3 RCT (NCT05306899) evaluating high-dose IV ketamine for chronic daily headaches at Toronto Western Hospital and Sinai Health System. The trial targets NMDA receptor-mediated central sensitization underlying refractory headache disorders.

1 trial
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United States

Portland Institute for Psychedelic Science

The Portland Institute for Psychedelic Science (PIPS) is a US-based research-oriented institute supporting psychedelic science initiatives, program development, and practice-adjacent translational work.

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United States

Portland Psychotherapy

Other

Portland Psychotherapy is a Portland, Oregon clinic, research, and training center that integrates psychedelic science into evidence-based clinical practice, conducting clinical trials of MDMA-assisted therapy for social anxiety disorder and offering psychedelic integration services. Their distinctive model funds peer-reviewed research through clinical revenue, resulting in exceptionally well-trained therapists in psychedelic-assisted care.

2 trials
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United States

Portland VA Research Foundation, Inc

Non-Profit

The Portland VA Research Foundation, Inc. is a non-profit entity supporting clinical research at the Portland VA Health Care System in Oregon. It sponsors the SNaP Lab's psilocybin-enhanced psychotherapy trial for methamphetamine use disorder (with the Cohen Foundation) and the Group-MVP MDMA group therapy trial for Veterans with PTSD, both led by Dr. Christopher Stauffer, an OHSU Associate Professor of Psychiatry.

2 trials
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Canada

Providence Care Hospital, Kingston, ON, Canada

Other

Providence Care Hospital in Kingston, Ontario hosts Canada's first hospital-based psychedelic research centre — the Centre for Psychedelics Health and Research (opened 2024) — in partnership with Queen's University and CAN-BIND, conducting psilocybin and LSD research alongside its established IV ketamine clinic for treatment-resistant depression led by Dr. Claudio Soares.

1 trial
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Canada

Psilo Scientific Ltd

Subsidiary

Psilo Scientific Ltd is a Health Canada-licensed psilocybin producer and wholly-owned subsidiary of Filament Health Corp (NEO: FH), supplying purified botanical psilocybin (PEX010) to clinical trials including the PSYCHED-PAL palliative care microdosing study; it also licensed PEX010 to Cybin for Phase 2 trials in treatment-resistant depression and alcohol use disorder.

1 trial
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Australia

Psychedelic Research in Science & Medicine (PRISM)

PRISM is an Australian nonprofit organization advancing evidence-based psychedelic science, policy, and public education through research communication, expert engagement, and policy-facing advocacy.

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Australia

Psyence Australia Pty Ltd

Subsidiary

Psyence Australia Pty Ltd is the Australian subsidiary of Psyence Biomed Ltd (Nasdaq: PBM), a company focused on nature-derived botanical psilocybin medicine; it received HREC approval to conduct a Phase IIb randomized double-blind trial evaluating natural psilocybin (NPX-5 at 10 mg and 25 mg) versus an active low-dose comparator for adjustment disorder in palliative care cancer patients, with sites in Melbourne and Perth.

1 trial
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United Kingdom

Psyrin Inc.

Other

Psyrin Inc. is a UK-based AI health startup founded by researchers from King's College London that develops speech analysis algorithms using machine learning to rapidly assess serious mental illness from brief voice recordings; its patent-pending technology achieved 86% accuracy distinguishing psychosis-spectrum disorders from other conditions in a Translational Psychiatry publication, and is being studied as a tool for predicting treatment response to psychiatric interventions.

1 trial
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China

Qinghai Red Cross Hospital

Other

Qinghai Red Cross Hospital (青海红十字医院) is a JCI-accredited 3A-grade comprehensive hospital with 2,000 beds in Xining, Qinghai Province, China, established in 1949 and the first hospital in western China to receive JCI accreditation; affiliated researchers are participating in clinical trials investigating intraoperative esketamine as a preventive treatment for postpartum depression following cesarean section.

1 trial
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Canada

Quantified Citizen Technologies Inc.

Other

Quantified Citizen Technologies Inc. is a Canadian privacy-centric mobile health research platform powering decentralized citizen-science studies; it built the world's first mobile app for psychedelic microdosing data collection (Microdose.me) with over 19,000 participants worldwide, whose findings were published in Nature Scientific Reports, and continues to host multiple psychedelic observational studies in partnership with MAPS, UBC, and researchers including Paul Stamets and James Fadiman.

1 trial
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United States

RIVER Foundation

Non-Profit

RIVER Foundation is a US-based nonprofit conducting observational research on ketamine treatment plans for chronic conditions, including an ongoing study led by a doctoral candidate in clinical psychology; through its Assimilation Program, it connects patients with licensed physicians who can prescribe home-based ketamine sessions with integration support.

1 trial
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United States

Rady Children's Hospital, San Diego

Other

Rady Children's Hospital San Diego is a leading US pediatric academic medical center with over 200 active clinical trials; its emergency department research team is studying whether a single low-dose IV ketamine infusion reduces depression symptoms and suicidal ideation in adolescents compared to placebo, aiming to expand rapid treatment options in the emergency setting.

1 trial
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Sweden

Region Örebro County

Other

Region Orebro County is a Swedish regional public health authority in central Sweden whose University Hospital (Universitetssjukhuset Orebro) is a participating site in the CAPSI trial, a randomized study investigating single-dose psilocybin-assisted psychotherapy for major depression in adult cancer patients.

1 trial
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Canada

Remedy

Other

Remedy is a Toronto-based mental health innovation community founded by Dr. Anne Wagner, C.Psych., that conducts psychedelic research through its Remedy Institute arm; Dr. Wagner leads two MDMA-assisted psychotherapy trials for PTSD — a pilot open-label study combining MDMA with Cognitive Processing Therapy (CPT), and a randomized controlled trial combining MDMA with Cognitive Behavioral Conjoint Therapy (CBCT), a couples therapy approach.

2 trials
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United States

Rett Syndrome Research Trust

Non-Profit

The Rett Syndrome Research Trust (RSRT) is a US-based nonprofit dedicated to curing Rett syndrome (RTT) that funded, held the IND for, and oversaw a randomized double-blind placebo-controlled crossover trial of oral ketamine in girls aged 6-12 with RTT; the study confirmed safety and tolerability and demonstrated EEG evidence of NMDA receptor target engagement, supporting further trials with longer duration or higher doses.

1 trial
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Denmark

Rigshospitalet, Denmark

Other

Copenhagen University Hospital Rigshospitalet is Denmark's foremost academic medical center, home to the Neurobiology Research Unit (NRU) led by Professor Gitte Moos Knudsen, which has conducted psychedelic neuroimaging research with psilocybin and LSD since 2017; its affiliated NOESIS clinical research unit runs active trials investigating psilocybin for depression, OCD, and cancer-related distress, plus LSD serotonin 2A receptor occupancy imaging studies, in collaboration with Imperial College London and Karolinska Institutet.

2 trials
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Canada

Rose Hill

Private Biotech

Rose Hill Life Sciences is a North American psychedelic life sciences company that supplies research-grade Psilocybe cubensis biomass and sponsors clinical trials, including the PHATHOM study testing psilocybin combined with physical therapy to restore motor function in stroke patients; it also collaborates with Johns Hopkins, the University of Guelph, and the Canadian Centre for Psychedelic Science, and has operated a psilocybin mushroom cultivation facility since 2015.

1 trial
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Australia

Royal North Shore Hospital

Other

Royal North Shore Hospital (RNSH) in St Leonards, New South Wales, Australia is a major academic medical center within the Northern Sydney Local Health District; its CADE Clinic (Department of Psychiatry) and Northern Sydney Anaesthetic Research Institute have participated in multiple ketamine trials including the KADS Phase 3 RCT of subcutaneous racemic ketamine for treatment-resistant depression, and real-world esketamine studies for depression management.

1 trial
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Canada

Réseau québécois sur le suicide, les troubles de l'humeur et les troubles associés

Other

The Quebec Network on Suicide, Mood Disorders and Associated Disorders (RQSHA) is a publicly-funded interdisciplinary research network supported by the Fonds de recherche du Québec that brings together researchers from across Quebec to study suicide, mood disorders, and substance use; it has funded several ketamine trials including the 'Montreal Model' study integrating psychedelic-informed ketamine therapy with psychological support for severe treatment-resistant depression, and research on music as an intervention to improve ketamine tolerability in depression treatment.

1 trial
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SUNY New Paltz

SUNY New Paltz (State University of New York at New Paltz) is a public university in New Paltz, New York, that is part of the SUNY system. It offers undergraduate and graduate programs across the arts, sciences, education, and professional fields.

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Canada

Salem Anaesthesia Pain Clinic

Other

Salem Anaesthesia Pain Clinic is an outpatient anesthesia and pain management clinic in Surrey, British Columbia, led by Dr. Olu Bamgbade, a clinical assistant professor with over 25 years of experience in the UK, USA, and Canada; the clinic offers IV ketamine infusion for treatment-resistant depression, mood disorders, and chronic pain, and has conducted clinical research demonstrating that ketamine enhances both analgesia and mood outcomes in chronic pain patients.

1 trial
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Canada

Saskatoon Health Region

Other

The Saskatoon Health Region (now integrated into the Saskatchewan Health Authority) was the regional health authority responsible for hospital and community health services in Saskatoon and surrounding areas in Saskatchewan, Canada; through Royal University Hospital, it supported pioneering ketamine research for psychiatric conditions including comparative ECT and ketamine anesthesia trials, and the intranasal racemic ketamine protocol for hospitalized patients with treatment-resistant depression developed by Dr. Evyn Peters.

1 trial
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United States

Shenox Pharmaceuticals, LLC

Private Biotech

Shenox Pharmaceuticals LLC is a US-based specialty pharmaceutical company developing innovative transdermal delivery systems for psychiatric medications; their lead program SHX-001 is a ketamine transdermal patch that delivers sustained, controlled ketamine plasma concentrations for up to 7 days to treat major depressive disorder while minimizing the adverse effects, abuse potential, and clinic-visit burden of IV and intranasal ketamine, with FDA IND approval granted in 2018 and an ongoing Phase 1 pharmacokinetics and antidepressant efficacy trial.

1 trial
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United States

Sheppard Pratt Health System

Other

Sheppard Pratt Health System is a leading non-profit psychiatric hospital and health system in Towson, Maryland, home to the Center of Excellence for Psilocybin Research and Treatment — the first international center of its kind — established in partnership with COMPASS Pathways; it has conducted landmark psilocybin trials including the first trial for bipolar type II depression (published in JAMA Psychiatry with 80% remission at 12 weeks), psilocybin for treatment-resistant depression (published in NEJM), and psilocybin for TRD with chronic suicidal ideation.

3 trials
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United Kingdom

Small Pharma Ltd

Private Biotech

Small Pharma Ltd was a UK-based psychedelic biotechnology company that conducted the world's first clinical trials of DMT-assisted therapy for major depressive disorder; their lead compound SPL026 (N,N-dimethyltryptamine fumarate) delivered a short-lived ~20-minute psychedelic experience via IV or IM administration, and the Phase I/IIa program in collaboration with Imperial College London's Centre for Psychedelic Research demonstrated consistent quality of psychedelic response and antidepressant effects; the company was subsequently acquired by Cybin Inc. to create the industry's largest deuterated DMT program.

3 trials
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United States

Soterix Medical

Private Biotech

Soterix Medical is a US-based medical device company specializing in non-invasive neuromodulation technology, primarily transcranial direct current stimulation (tDCS); the company develops tDCS devices used in clinical research trials for treatment-resistant depression, bipolar depression, and substance use disorders, and has contributed to ketamine biomarker validation research exploring how neuromodulation biomarkers can predict or complement ketamine treatment response in patients with major depressive disorder.

1 trial
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United Kingdom

South London and Maudsley NHS Foundation Trust

Other

South London and Maudsley NHS Foundation Trust (SLaM) is the UK's leading academic mental health Trust, home to Maudsley Hospital and the NIHR Maudsley Biomedical Research Centre; in partnership with COMPASS Pathways and King's College London's Institute of Psychiatry, it has established a dedicated Psychedelics and Mental Health Research Centre conducting psilocybin Phase 3 trials for treatment-resistant depression, MDMA therapy for PTSD, 5-MeO-DMT studies, and the SIGNATURE synaptic imaging biomarker trial, aiming to treat 650–700 patients over five years.

2 trials
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Australia

South West Sydney Local Health District

Other

South West Sydney Local Health District (SWSLHD) is a large public health network serving south-west Sydney, New South Wales, Australia; it has participated in cutting-edge psychedelic research trials including KET-DUAL, a pilot study of ketamine-enhanced therapy for patients with co-occurring alcohol use disorder and depression, and MPATHY, an RCT of MDMA-assisted prolonged exposure therapy for comorbid alcohol use disorder and post-traumatic stress disorder.

2 trials
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United States

Spaulding Rehabilitation Hospital

Other

Spaulding Rehabilitation Hospital is a leading rehabilitation hospital in Boston, Massachusetts, affiliated with the Mass General Brigham health system and home to the Scott Schoen and Nancy Adams Discovery Center for Chronic Pain Recovery. It is pioneering psychedelic research in pain medicine through the first clinical trial of MDMA-assisted therapy for fibromyalgia, which uses hyperscan neuroimaging to investigate how MDMA influences brain-to-brain dynamics between patient and therapist to produce analgesia, in collaboration with PharmAla Biotech.

1 trial
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United States

Special Operators Care Fund

Non-Profit

The Special Operations Care Fund (SOC-F) is a US non-profit organization based in Atlanta, Georgia, that provides direct support to active and retired members of the Special Operations Forces community and their families. It is the sponsor of the Trifecta Research Study — conducted with Johns Hopkins Center for Psychedelic and Consciousness Research — which investigates hormone replacement therapy, magnetic e-resonance therapy (MeRT), ibogaine, and 5-MeO-DMT in combination for the treatment of PTSD and TBI-related cognitive impairment in SOF veterans.

1 trial
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Switzerland

Spital Uster AG, Uster, Switzerland

Other

Spital Uster AG is a community hospital in Uster, Switzerland, whose Department of Medicine is affiliated with palliative care physician Sivan Schipper — a member of the Swiss Medical Society for Psycholytic Therapies (SÄPT). Schipper co-authored the landmark Cochrane systematic review of psychedelic-assisted therapy for anxiety, depression, and existential distress in patients with life-threatening diseases, and Spital Uster is associated with Switzerland's LSD-in-palliative-care research program investigating LSD-assisted therapy for anxiety in patients with life-threatening illness.

1 trial
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Ireland

St Patrick's Hospital, Ireland

Other

St Patrick's Mental Health Services (SPMHS) is Ireland's largest independent not-for-profit mental health hospital, located in Dublin, and a leading centre for ketamine research in Ireland. In collaboration with Trinity College Dublin's Professor Declan McLoughlin, it has run the KITE-Dep study (ketamine interleaved with ECT), the KARMA-Dep pilot RCT, and the definitive KARMA-Dep-2 randomised clinical trial — the most rigorous investigation of repeated IV ketamine infusions as adjunctive inpatient therapy for major depression conducted in Ireland.

4 trials
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Canada

St. Joseph's Healthcare Hamilton

Other

St. Joseph's Healthcare Hamilton (SJHH) is a multi-site academic health sciences centre in Hamilton, Ontario, Canada, home to the new Centre for Health Innovation and Research in Psychedelics — one of Canada's first dedicated psychedelic research centres. It serves as a test site for the PSYCHED-PAL trial investigating psilocybin microdosing for psychological and existential distress in palliative care patients, and is also conducting trials of psilocybin for cannabis use disorder and chronic pain, with plans to study ketamine, MDMA, and DMT across a broad range of therapeutic indications.

1 trial
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United States

Sunstone Medical

Private Biotech

Sunstone Medical (operating as Sunstone Therapies) is a US-based clinical-stage organization headquartered in Rockville, Maryland, that focuses on developing and delivering psychedelic-assisted therapy in the medical setting at its purpose-built Bill Richards Center for Healing at Adventist HealthCare Shady Grove Medical Center. It runs trials of psilocybin for major depression in adults with cancer (in collaboration with COMPASS Pathways and Johns Hopkins), MDMA-assisted therapy for adjustment disorder in cancer patient-caregiver dyads, and psilocybin for sexual assault-related PTSD (SUN004).

3 trials
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Australia

Sydney

Other

The University of Sydney is Australia's oldest university, founded in 1850, with internationally recognized research programs in medicine, pharmacy, and addiction medicine. Its Faculty of Medicine and Health contributes to cutting-edge ketamine research, including as a collaborating institution in the KET-DUAL pilot study — investigating ketamine-enhanced therapy for individuals with co-occurring alcohol use disorder and depression — conducted through the Drug Health Services at Royal Prince Alfred Hospital in Sydney.

1 trial
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Taiwan

Taipei Veterans General Hospital, Taiwan

Other

Taipei Veterans General Hospital (TVGH) is a prestigious tertiary-care academic hospital in Taipei, Taiwan, and home to the Precision Depression Intervention Center (PreDIC) — one of Asia's leading centers for ketamine and esketamine treatment of depression. TVGH has conducted pioneering studies of dose-related adjunctive ketamine for genotyped Taiwanese patients with treatment-resistant depression, low-dose ketamine for TRD with prominent suicidal ideation, and low-dose ketamine infusion for adolescents with treatment-resistant depression.

2 trials
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The New School for Social Research

The New School for Social Research is the graduate division of The New School in New York City, offering advanced degrees and research in the social sciences, philosophy, and history. It is known for progressive, interdisciplinary scholarship and a history rooted in the University in Exile that supported scholars fleeing fascism in the 1930s.

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UC San Francisco

A leading public research university and health sciences campus in San Francisco, California, part of the University of California system. UCSF is renowned for its medical school, research hospitals, and institutes conducting breakthrough research across neuroscience, psychiatry, oncology, and pharmacology, including emerging work on psychedelic-assisted therapies.

1 trial
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UT Health

UTHealth Houston (UT Health) is the health sciences center of the University of Texas System, located in Houston, Texas. It encompasses schools of medicine, public health, dentistry, nursing, and biomedical sciences, conducting clinical and translational research across psychiatry, neuroscience, and substance use disorders with a focus on improving the health of diverse communities.

1 trial
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Canada

Unity Health Toronto

Other

Toronto-based health system anchored by St. Michael's Hospital and St. Joseph's Health Centre. The Pinnacle Research Group at St. Michael's is running first-of-its-kind MDMA, ketamine, and psilocybin trials for chronic neuropathic pain, establishing Unity Health Toronto as a leading Canadian centre for psychedelic research.

5 trials
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Universidade Estadual de Campinas (UNICAMP)

Universidade Estadual de Campinas (UNICAMP) is a major Brazilian public research university with active psychedelic and mental-health research collaborations, including ICARO (Interdisciplinary Cooperation for Ayahuasca Research and Outreach), which supports ayahuasca-related scientific and translational work.

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Universidade Estadual de Feira de Santana

Universidade Estadual de Feira de Santana is a public Brazilian university with research activity spanning health and behavioral sciences, including work connected to psychedelic research networks.

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Universitat Autònoma de Barcelona

Universitat Autonoma de Barcelona is a major public research university in Spain with psychiatry and neuroscience programs that have contributed to psychedelic and psychopharmacology research.

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Universitat Politècnica de Catalunya

Universitat Politecnica de Catalunya is a public university in Barcelona with interdisciplinary scientific capacity that contributes to collaborative research initiatives, including health data and neuroscience-adjacent projects.

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Netherlands

University Groningen

Other

The University of Groningen's medical center (UMCG) is a leading European hub for psychedelic research, coordinating the EU-funded €6.5M PsyPal clinical trial studying psilocybin for psychological distress in palliative care patients. UMCG also hosts an annual interdisciplinary summer school in psychedelic research in collaboration with the OPEN Foundation and partner universities.

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United States

University of Alabama at Birmingham

Other

Major research university and academic medical center in Birmingham, Alabama. A key site in the first federally funded psilocybin trial in 50 years — a NIH/NIDA-funded multisite study on psilocybin for smoking cessation led by Dr. Peter Hendricks, alongside Johns Hopkins and NYU.

6 trials1 paper
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Netherlands

University of Amsterdam

Other

The University of Amsterdam (UvA) is one of the Netherlands' leading research universities, with its Amsterdam UMC Department of Psychiatry conducting clinical trials on psilocybin and psychedelic-assisted therapies for treatment-resistant mental health conditions.

54 trials
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United States

University of Pennsylvania

Other

The Penn Psychedelics Collaborative at the University of Pennsylvania is a multi-school consortium of researchers, clinicians, and faculty advancing transdisciplinary psychedelic science across Penn Medicine and Penn Nursing, including clinical trials of MDMA-assisted therapy and psilocybin research. Penn researchers are also leading the development of bioethical guidelines for psychedelic-assisted therapy and community implementation frameworks.

1 trial
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United States

University of Wisconsin-Madison

The University of Wisconsin-Madison Transdisciplinary Center for Research in Psychoactive Substances is dedicated to exploring the scientific, historical, and cultural aspects of psychoactive substances, focusing on psychedelics.

10 trials
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Canada

Vancouver Island University

In response to the fallout from the COVID-19 pandemic, a research group at Vancouver Island University (VIU) has been awarded funding from the Canadian Institutes of Health Research for the exploration of psychedelic therapies for front-line workers. Led by Dr Shannon Dames, the team are currently focusing on ketamine-assisted therapy for front-line workers experiencing symptoms of PTSD and emotional distress as a result of their experiences working through the pandemic.

2 trials
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United States

atai Therapeutics, Inc.

Public Biotech

atai Life Sciences (operating as atai Therapeutics, Inc. in the US) is a publicly traded clinical-stage biopharmaceutical company founded in 2018 with the largest and most diverse portfolio of psychedelic-derived drug candidates, including DMT, R-MDMA, psilocin, 5-MeO-DMT (BPL-003), and ibogaine for depression, anxiety, and addiction. Following its 2024 merger with Beckley Psytech to form AtaiBeckley, BPL-003 received FDA Breakthrough Therapy designation for treatment-resistant depression with Phase 3 trials anticipated in 2026.

2 trials
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