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Hunan Provincial Maternal and Child Health Care Hospital is a Class-III Grade-A specialist maternity and pediatric hospital in Changsha, Hunan Province, China, founded in 1947 with over 1,050 beds and 10,000 births annually. The hospital’s anesthesiology team is a leader in esketamine obstetrics research, including a landmark BMJ randomised trial (NCT04414943) showing a single low-dose esketamine infusion after childbirth reduced major postpartum depression at 42 days by approximately three-quarters in mothers with prenatal depression.

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