Major Depressive Disorder (MDD)Depressive DisordersSubstance Use Disorders (SUD)Public Health, Prevention & Behaviour ChangePsilocybin

Classic Psychedelics as a Psychotherapeutic Aid in the Treatment of Stimulant Use Disorder: a Case Report

This case study (2020) describes a 22-year-old male with a history of mood disorder and polysubstance use who decided to seek out psychotherapy for the first time following consumption of 3.5 grams of psilocybin-containing mushrooms. As treatment progressed, the patient reported being better able to consolidate his therapeutic gains through the integration of insights obtained through his use of classic psychedelics, ultimately remaining abstinent from all stimulant drugs.

Authors

  • Johnson, S.
  • Black, Q. C.

Published

International Journal of Mental Health and Addiction
individual Study

Abstract

Despite nascent research supporting the efficacy of classic psychedelics as a psychotherapeutic aid for the treatment of substance abuse, to date, there is limited published research exploring their use in the treatment of stimulant use disorder and dual diagnosis. A 22-year-old male with a history of mood disorder and polysubstance use presented to a private Australian mental health clinic. While undergoing psychological treatment for mood and stimulant use disorder, this patient reported significant benefit from his use of classic psychedelics. Following consumption of 3.5 grams of psilocybin-containing mushrooms, he decided to seek out psychotherapy for the first time. Throughout treatment, subjective reports of his classic psychedelic use, which among others, included two occasions of having consumed 200 μg of lysergic acid diethylamide and 100 mg of dimethyltryptamine, were recorded and a psychometric tool used to capture mystical experiences was administered. As treatment progressed, the patient reported being better able to consolidate his therapeutic gains through the integration of insights obtained through his use of classic psychedelics, ultimately remaining abstinent from all stimulant drugs. The results of this case report suggest that classic psychedelics may be effective psychotherapeutic aids to be used in traditional substance abuse treatment programs. It is hoped that this case report will inform future research in this field.

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Research Summary of 'Classic Psychedelics as a Psychotherapeutic Aid in the Treatment of Stimulant Use Disorder: a Case Report'

Introduction

Earlier research has begun to show potential for classic psychedelics as an aid in treating substance use disorders, but evidence specifically addressing stimulant use disorder and people with co-occurring psychiatric diagnoses is scarce. Observational and survey data have suggested reductions in stimulant misuse and cravings after psychedelic experiences, and mechanistic work is beginning to map neurobiological effects; nevertheless, no peer-reviewed clinical studies had examined classic psychedelic-assisted therapy for stimulant use disorder at the time of this report. Methamphetamine and other psychostimulant problems are described as an international public health challenge, with limited pharmacological treatment options and prolonged cognitive and emotional difficulties following abstinence. This paper seeks to explore the therapeutic potential of classic psychedelics in assisting treatment for stimulant use disorder with co-occurring depression by presenting a single-patient case report. Using the clinical course and self-reported experiences of a 22-year-old man in treatment for major depressive disorder and stimulant dependence, the authors aim to describe how classic psychedelic use intersected with engagement in psychotherapy, changes in substance use, and measures of mystical-type experience, and to identify directions for future research in this area.

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Study Details

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